Ongina was one of the original nine contestants for the first season of RuPaul's Drag Race (also known as The Lost Season), as well as RuPaul's Drag Race Allstars Season 5. She also made five appearances in the first and second season of RuPaul's Drag U. Ongina broke several barriers for the franchise - from being a bald queen, the first AAPI contestant on the show, and one of the first reality TV stars to come out as HIV-positive on screen.

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Since coming out as HIV-positive she has used her platform to advocate for awareness for HIV testing and prevention, trans rights, and LGBTQ+ equality. She was the host for the online web show HIV and Me, a talk show featuring interviews with different individuals on how they live with HIV/AIDS. Ongina also was a spokesperson for OraQuick, one of the first at-home HIV testing kits, and amfAR’s online video series, Epic Voices - Countdown to the Cure Campaign which aims to reenergize the response to HIV among Millennial and LGBTQ+ communities.  The campaign also aims to renew awareness of the persistent threat of HIV, the urgent need to support HIV research and amFAR's leadership in the search for a cure. In 2021, Ongina was the host of The Walk Show for the Los Angeles AIDS Walk, and was featured in an accompanied televised special, Localish LA AIDS Walk Special.